Nov 17, · The IL23/IL17 axis is an important pathway for targeted therapy for inflammatory diseases Emerging evidence from clinical trials has shown that monoclonal antibodies against IL23, IL17, and tumor necrosis factor are effective in the treatment of patients with psoriasis, atopic dermatitis, hidradenitis suppurativa, pityriasis rubra pilarisJun 29, 15 · Two IL23–specific antagonists, tildrakizumab (MK3222;Dec 22, 15 · Interestingly, IL12/IL23 pathways, which have been known to play an important role in the pathogenesis of psoriasis 22,23, have been also found to be dysregulated in hepatitis C and may contribute to HCVmediated inflammatory damage and progression of
The Il 23 Th17 Axis In The Immunopathogenesis Of Psoriasis Sciencedirect